How to Use μLED Optoelectrodes? Surgery, Data Collection and μLED Control

Abstract

Optogenetics are a powerful tool for testing how a neural circuit influences neural activity, cognition, and behavior. Accordingly, the number of studies employing optogenetic perturbation has grown exponentially over the last decade. The recent introduction of μLED silicon probes, which feature independently controllable miniature LEDs embedded at several levels of each of multiple shanks of silicon probes, provides a tractable method for temporally and spatially precise interrogation of neural circuits. Here, we provide a protocol addressing how to perform chronic recordings using μLED probes.

Mihály Vöröslakos

Postdoctoral Researcher

My research interests include translational neuroscience, non-invasive brain stimulation and neuroscience tool development.