HectoSTAR μLED Optoelectrodes for Large‐Scale, High‐Precision In Vivo Opto‐Electrophysiology

Abstract

Dynamic interactions within and across brain areas underlie behavioral and cognitive functions. To understand the basis of these processes, the activities of distributed local circuits inside the brain of a behaving animal must be synchronously recorded while the inputs to these circuits are precisely manipulated. Even though recent technological advances have enabled such large-scale recording capabilities, the development of the high-spatiotemporal-resolution and large-scale modulation techniques to accompany those recordings has lagged. A novel neural probe is presented in this work that enables simultaneous electrical monitoring and optogenetic manipulation of deep neuronal circuits at large scales with a high spatiotemporal resolution.

Mihály Vöröslakos

Postdoctoral Researcher

My research interests include translational neuroscience, non-invasive brain stimulation and neuroscience tool development.