A Battery-Powered Opto-Electrophysiology Neural Interface with Artifact-Preventing Optical Pulse Shaping

Adam E. Mendrela, Sung-yun Park, Mihály Vöröslakos, Michael P. Flynn, Euisik Yoon
Posted January, 2018
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Abstract

We present a neural interface IC for high-precision optical stimulation and electrical recording from implanted optoelectrodes with the highest system integration to date. The system combines 12 high-resolution constant-current LED driver channels, 32 recording channels, and an efficient PMU for operation from a low voltage Li battery on a wireless platform. A novel LED driver architecture features a high-efficiency wide-current-range fully-integrated voltage regulator and a high-resolution pulse shaper to minimize recording artifacts from sharp current pulse edges. A prototype, fabricated in 0.18$μ$m CMOS, occupies 7.35mm2. The LED driver has a peak efficiency of 50% and consumes 31$μ$W quiescent power. We demonstrate in-vivo that the pulse-shaping scheme prevents stimulation artifacts. Key Words: neural interface, LED driver, optogenetics.

Type
Conference paper
Publication
IEEE Symposium on VLSI Circuits, Digest of Technical Papers
Mihály Vöröslakos
Mihály Vöröslakos
Postdoctoral Researcher

My research interests include translational neuroscience, non-invasive brain stimulation and neuroscience tool development.